College Football Best Bets | September 26, 2026
College football best bets for September 26, 2026 with eight sides and totals.

Saturday, September 26 brings one of the strongest college football boards of the young season.
CTS Best Bets
Tennessee +4.5 vs. Texas
Texas faces its first true road test at Neyland. Tennessee has scored 47.7 points per game while allowing 14.0, giving us enough reason to take more than a field goal at home.
Iowa-Michigan Under 38.5
Iowa has allowed 4.3 points and 176.7 yards per game. Michigan has allowed 13.0 points and roughly 220 yards per game. We prefer the Under to choosing a side.
Florida -3.5 vs. Ole Miss
Ole Miss comes off an emotional LSU win and now travels to Gainesville. We are comfortable laying less than four with Florida at home.
Ole Miss-Florida Over 58.5
Ole Miss has already shown explosive SEC offense, and Florida has enough playmakers to contribute rather than asking one side to carry the total.
USC +3 vs. Oregon
USC has scored at least 39 points in every game and averages more than 340 passing yards. We want the field goal at home.
Oregon-USC Under 61.5
The total has climbed from the high 50s into the low 60s. We would rather sell the inflated shootout number.
Texas A&M +9.5 at LSU
The market has moved dramatically toward LSU. Nearly double digits gives us enough cushion to back A&M and Marcel Reed’s mobility.
Missouri-Mississippi State Over 58.5
Both offenses have enough quarterback play and explosive ability to push this beyond four touchdowns per side.
CTS Card
Tennessee +4.5
Iowa-Michigan Under 38.5
Florida -3.5
Ole Miss-Florida Over 58.5
USC +3
Oregon-USC Under 61.5
Texas A&M +9.5
Missouri-Mississippi State Over 58.5
